OpenMS

OpenMS is an open-source software C++ library for LC-MS data management and analyses. It offers an infrastructure for rapid development of mass spectrometry related software. OpenMS is free software available under the three clause BSD license and runs under Windows, macOS, and Linux.

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What OpenMS can do for you

It comes with a vast variety of pre-built and ready-to-use tools for proteomics and metabolomics data analysis (TOPPTools) as well as powerful 1D, 2D and 3D visualization (TOPPView).

OpenMS offers analyses for various quantitation protocols, including label-free quantitation, SILAC, iTRAQ, TMT, SRM, SWATH, etc.

It provides built-in algorithms for de-novo identification and database search, as well as adapters to other state-of-the art tools like X!Tandem, Mascot, Comet, etc. It supports easy integration of OpenMS built tools into workflow engines like KNIME, Galaxy, WS-Pgrade, and TOPPAS via the TOPPtools concept and a unified parameter handling via a 'common tool description' (CTD) scheme.

With pyOpenMS, OpenMS offers Python bindings to a large part of the OpenMS API to enable rapid algorithm development. OpenMS supports the Proteomics Standard Initiative (PSI) formats for MS data. The main contributors of OpenMS are currently the Eberhard-Karls-Universität in Tübingen, the Freie Universität Berlin, and the ETH Zürich.

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Keywords
Programming languages
  • C++ 82%
  • MAXScript 6%
  • CMake 4%
  • Cython 4%
  • Python 2%
  • NSIS 1%
  • Other 1%
License
</>Source code

Participating organisations

Canarie
Digital Research Alliance of Canada
OpenMS

Mentions

Contributors

Contact person

HR

Hannes L Röst

Principal Investigator
Mail Hannes L
HR
Hannes L Röst
Principal Investigator
SA
Stephan Aiche
CB
Chris Bielow
HW
Hendrik Weisser
FA
Fabian Aicheler
SA
Sandro Andreotti
HE
Hans-Christian Ehrlich
EK
Erhan Kenar
XL
Xiao Liang
SN
Sven Nahnsen

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