MUSCLE3
MUSCLE3 is a coupling library for building multiscale simulations out of single-scale models.
Python library for YAML type inference, schema checking and syntactic sugar.
YAML-based file formats can be very handy, as YAML is easy to write by humans, and parsing support for it is widely available. Just read your YAML file into a document structure (a tree of nested dicts and lists), and manipulate that in your code.
While this works fine for simple file formats, it does not scale very well to more complex file formats such as the Common Workflow Language (CWL) or the Multiscale Computing Language (yMCL). Manual error-checking is lots of work and error-prone, defaults are not set automatically (which is especially tricky if you have multiple nested optional objects), and the file format often ends up somewhat underspecified.
Furthermore, a small collection of nested dicts and lists may work fine, but for more complex file formats, this becomes unwieldy and a set of objects is a better choice. Although it is not often used this way, YAML is actually a fully fledged object-to-text serialisation protocol. The Python yaml and ruamel.yaml libraries will actually construct objects for you, but the class names need to be put in the YAML file for that to work, which makes those files harder to read and write for humans.
YAtiML is a helper library that helps address these issues. With YAtiML, you have easy-to-read YAML for the user, and easy-to-use objects for the programmer, with validation and automatic type recognition in between.
Sustaining and improving the MUSCLE3 model coupling framework
Identification and prioritization of cancer-causing structural variations in whole genomes
Enhancing multiscale computing with sensitivity analysis and uncertainty quantification
Combining molecular simulation and eScience technologies
MUSCLE3 is a coupling library for building multiscale simulations out of single-scale models.
Highly portable parallel workflow to generate artificial genomes with structural variants.