A Distributed Data Management System and Scientific Gateway for Mining Next Generation Sequence Data from Immune Responses.
iReceptor is a data discovery platform that facilitates the curation, analysis and sharing of antibody/B-cell and T-cell receptor repertoires (Adaptive Immune Receptor Repertoire or AIRR-seq data) from multiple labs and institutions. We are committed to providing a platform for researchers to increase the value of their data through sharing with the community. This will greatly increase the amount of data available to answer complex questions about the adaptive immune response, accelerating the development of vaccines, therapeutic antibodies against autoimmune diseases, and cancer immunotherapies. Visit the COVID-19 page for a list of curated COVID-19 AIRR-seq studies.
The iReceptor Gateway integrates large, distributed, AIRR-seq data repositories, following standards for sharing and interoperability developed by the Adaptive Immune Receptor Repertoire (AIRR) Community. The main goal of iReceptor is to connect this distributed network of AIRR-seq repositories into an AIRR Data Commons, allowing queries across multiple projects, labs, and institutions.
Present functionalities include:
iReceptor is a member of the iReceptor Plus Consortium. This project will expand the analysis tools available on the Gateway, including for single cell or systems immunology approaches, and add security for iReceptor Plus repositories.
Users of the iReceptor Gateway can search AIRR-seq data from studies on ovarian cancer, autoimmune diseases such as MS and SLE, and infectious diseases such as COVID-19 and HIV. Visit the iReceptor Studies page for a list of curated studies.
iReceptor Turnkey - Source code
iReceptor Service (PHP/MongoDB) - Source code
iReceptor Data Migration Service - Source code
iReceptor Database Service - Source code
iReceptor AIRR Mapping Configuration File - Source code
iReceptor Data Curation - Source code
ireceptor Monitor - Source code