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Simulation code accompanying the publication "Cohesin supercoils DNA during loop extrusion"

Simulation code accompanying the publication "Cohesin supercoils DNA during loop extrusion"

1
contributor

Description

Research objective: computationally determine the linking number of plasmids after SMC-mediated DNA loop extrusion with twist and topoisomerase-mediated Lk change

Type of research: Comparison of computational model to experimental bulk plasmid assays

Method of data collection: 1D Monte Carlo simulations

Type of data: custom python code (.py) and .json data file

Logo of Simulation code accompanying the publication "Cohesin supercoils DNA during loop extrusion"
Keywords
Cohesin
DNA loop extrusion
DNA supercoiling
Monte Carlo simulation
plasmid assay
License
  • CC-BY-NC-SA-4.0
</>Source code
Not specified
Packages

Contributors

RB
Roman Barth

Member of community

4TU