Simulation code accompanying the publication "Cohesin supercoils DNA during loop extrusion"

Simulation code accompanying the publication "Cohesin supercoils DNA during loop extrusion"

1
contributor

Description

Research objective: computationally determine the linking number of plasmids after SMC-mediated DNA loop extrusion with twist and topoisomerase-mediated Lk change

Type of research: Comparison of computational model to experimental bulk plasmid assays

Method of data collection: 1D Monte Carlo simulations

Type of data: custom python code (.py) and .json data file

Logo of Simulation code accompanying the publication "Cohesin supercoils DNA during loop extrusion"
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License
  • CC-BY-NC-SA-4.0
</>Source code
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Contributors

RB
Roman Barth

Member of community

4TU