Towards safety assessment based on human data. Imagine a world in which we perform precision safety testing of chemicals and pharmaceuticals without using laboratory animals. Imagine that the safety of chemicals and pharmaceuticals can be assessed for vulnerable groups such as infants, the elderly or the diseased. Imagine that we know how these substances interact with human biology and physiology and how they can be used safely at home, school or at work during the course of our lives. This is our vision for the future, the vision that underlies the development of the Virtual Human Platform for Safety Assessment, VHP4Safety.
VHP4Safety
Virtual Human Platform for Safety Assessment
Participating organisations
Med
Env
KWR
Nie
Impact
- 1.Author(s): Tessel B. Wijne, Wouter P.C. Boon, Anne S. Kienhuis, Ellen H.M. Moors, Jarno HoekmanPublished in NAM Journal by Elsevier BV in 2025, page: 10005010.1016/j.namjnl.2025.100050
- 2.Author(s): Lilas Courtot, Ellen Fritsche, Nina Hobi, Nicole Kleinstreuer, Robert Lee, Surat Parvatam, Merel Ritskes-Hoitinga, Clive Roper, Carl Westmoreland, Emeline GougeonPublished in NAM Journal by Elsevier BV in 2025, page: 10002710.1016/j.namjnl.2025.100027
- 3.Author(s): M. Teunis, E. Willighagen, O. Cinar, M. Martens, M. Klaassen, M. Liem, F. Hepkema, I. Djidrovski, A. Kienhuis, C. EveloPublished in Toxicology Letters by Elsevier BV in 2025, page: S29-S3010.1016/j.toxlet.2025.07.091
- 4.Author(s): M. Martens, S. Adil, J. Millán Acosta, E. WillighagenPublished in Toxicology Letters by Elsevier BV in 2025, page: S46610.1016/j.toxlet.2025.07.1074
- 5.Author(s): Holly M. Mortensen, Maciej Gromelski, Ginnie Hench, Marvin Martens, Clemens Wittwehr, Saurav Kumar, Vikas Kumar, Karine Audouze, Vassilis Virvilis, Penny Nymark, Michelle Angrish, Iseult Lynch, Stephen Edwards, Barbara Magagna, Marcin W. WojewodzicPublished in Computational Toxicology by Elsevier BV in 2025, page: 10036810.1016/j.comtox.2025.100368