Optical Coherence Tomography (OCT) provides microscopic 3D images of tissue. It has the potential of becoming a powerful diagnostic tool as evidenced by 1,600 published scientific papers this year. OCT is challenged to improve the resolution and gathering physiological information from the images. This is exactly what the Biomedical Engineering & Physics group (Academic Medical Center) and the Numeric Control for Optics group (Technical University of Delft) are funded to solve: create super-resolution functional OCT suitable for clinical use. We will be faced with a large amount of OCT-data. In this EYR4 proposal we describe how this prize will help us manage this challenge in a smart way which will be a huge contribution to our research and forms a template for a virtual diagnosis environment used by physicians.