SoftwareApplication
name: ValidSense
description: The ValidSense toolbox aims to assess the agreement between two quantitative methods using the Limits of Agreement analysis, aka the Bland-Altman analysis. Four existing variants are available. Moreover, a Longitudinal analysis is developed to assess agreement over time.
description: ## Description The ValidSense toolbox aims to assess the agreement between two quantitative methods or devices measuring the same quantity using the Limits of Agreement analysis (LoA analysis), also known as the Bland-Altman analysis, using four existing variants. Moreover, a Longitudinal analysis is developed to assess agreement over time. ## Usage ValidSense is a webbased application, consisting of five pages. Follow the instructions on these pages sequentially. Detailed instructions are given in the web interface. This is a summary of the usage of the five pages. 1. Introduction: Information about the ValidSense software and the statistical methods is given here 2. Loading: Files must be uploaded here, and some filtering settings can be made. Use CSV or XLSX files 3. Preprocessing: The analysis variant is chosen, as well as variables and settings. Variants available: - Limits of Agreement: - Classic: Assess agreement in single pair of measurements per patient, [Bland & Altman 1986](https://pubmed.ncbi.nlm.nih.gov/2868172/) - Repeated measurements: Assess agreement in multiple measurements per patient, [Bland & Altman 1999 section 5.2](https://pubmed.ncbi.nlm.nih.gov/10501650/), [Bland & Altman 2007 section 3](https://pubmed.ncbi.nlm.nih.gov/17613642/) - Mixed-effects: Assess agreement based on the mixed-effects LoA analysis, allowing to correct, for example, multiple measurements per patient or systematic relationship between the difference and mean, [Parker et al. 2016](https://pubmed.ncbi.nlm.nih.gov/27973556/) - Regression of difference: Assess agreement in a single measurement per patient, with a linear relationship between difference and mean for bias and/or LoA, [Bland & Altman 1999 section 3.2](https://pubmed.ncbi.nlm.nih.gov/10501650/) - Longitudinal analysis: a new method to assess agreement over time. 5. Limits of Agreement Analysis: The Bland-Altman plot is shown, along with information helping to check assumptions of the analysis 6. Longitudinal Analy…
code repository: https://github.com/umcu/ValidSense
author: https://orcid.org/0009-0009-6560-7827
author: https://orcid.org/0000-0003-1895-0998
author: https://orcid.org/0000-0002-9400-6125
author: https://orcid.org/0000-0001-7342-0741
keywords: Limits of Agreement
keywords: Agreement Analysis
keywords: Bland-Altman
keywords: Sensor Drift
programming language: Python
license:
  creative work: creativeWork
    name: MIT

https://orcid.org/0009-0009-6560-7827
type: Person
given name: Peter
family name: van 't Ooster
name: Peter van 't Ooster
role name: Developer Research Software and App
affiliation: Organization
  name: University of Twente

https://orcid.org/0000-0003-1895-0998
type: Person
given name: Teus
family name: Kappen
name: Teus Kappen
role name: Conceptualization and review
affiliation: Organization
  name: Universitair Medisch Centrum Utrecht

https://orcid.org/0000-0002-9400-6125
type: Person
given name: Sietse
family name: Rispens
name: Sietse Rispens
role name: FAIRify software
affiliation: Organization
  name: University Medical Center Utrecht

https://orcid.org/0000-0001-7342-0741
type: Person
given name: Martine
family name: Breteler
name: Martine Breteler
role name: Conceptualization and review
affiliation: Organization
  name: University Medical Center Utrecht