SoftwareApplication
name: Simulation code accompanying the publication "Cohesin supercoils DNA during loop extrusion"
description: Simulation code accompanying the publication "Cohesin supercoils DNA during loop extrusion"
description: Research objective: computationally determine the linking number of plasmids after SMC-mediated DNA loop extrusion with twist and topoisomerase-mediated Lk change Type of research: Comparison of computational model to experimental bulk plasmid assays Method of data collection: 1D Monte Carlo simulations Type of data: custom python code (.py) and .json data file
author: Person
  given name: Roman
  family name: Barth
  name: Roman Barth
keywords: DNA loop extrusion
keywords: plasmid assay
keywords: Cohesin
keywords: DNA supercoiling
keywords: Monte Carlo simulation
license:
  creative work: creativeWork
    name: CC-BY-NC-SA-4.0